生化汤联合益母草颗粒促进产后子宫复旧的临床研究

文章信息/Info

• Title:生化汤联合益母草颗粒促进产后子宫复旧的临床研究

• 卷期:2024年22卷16期

• 作者:肖淑菁

• 江西省万安县妇幼保健院妇产科  江西吉安  343800

• Author(s):Xiao Shujing

• Department of Obstetrics and Gynecology, Wan 'an Maternal and Child Health Hospital of Jiangxi Province, Ji 'an 343800, China

• 关键词生化汤；益母草颗粒；子宫复旧；临床研究

• Keywords: Shenghua Decoction; Leonurus heterophyllus granules; Uterine involution; clinical research

• 摘要:目的 探讨生化汤联母草颗粒对产妇产后子宫复旧的影响。方法 选取2022年1月-2022年10月我院收治的60例自然分娩产妇为研究对象，随机分为观察组（n=30）与对照组（n=30）。对照组产妇采用益气凉血安宫汤进行治疗，观察组产妇在对照组的基础上给予生化汤联合益母草颗粒进行治疗，分析并比较2组产妇的中医证候疗效、子宫三径之和及宫底高度、恶露持续时间、生活质量及不良反应。结果 观察组产妇中医证候总有效率明显高于对照组（P＜0.05）；观察组产妇子宫三径之和及宫底高度均低于对照组（P＜0.05）；观察组产妇的血性恶露及浆液性恶露持续时间均明显短于对照组（P＜0.05）；观察组产妇的生活质量评分明显高于对照组（P＜0.05）；2组产妇不良反应发生率无明显差异（P＞0.05）。结论 生化汤联合益母草颗粒有助于促进产妇产后子宫复旧，安全性高，具有一定的临床应用价值。                                                                                                                                                                                

• Abstract To investigate the effect of Shenghua Tang Lianmu Cao Granule on postpartum uterine involution. Methods A total of 60 parturients with spontaneous delivery in our hospital from January 2022 to October 2022 were selected as the research objects, and randomly divided into the observation group (n=30) and the control group (n=30). The control group parturients were treated with Yiqi Liangxue Angong Decoction, and the observation group parturients were treated with Shenghua Decoction combined with Yimucao Granules on the basis of the control group. The curative effect of TCM syndromes, the sum of three uterine diameters, the height of the fundus, the duration of lochia, the quality of life and adverse reactions of the two groups of parturients were analyzed and compared. Results The total effective rate of the observation group was significantly higher than that of the control group (P＜0.05); The sum of three uterine diameters and the height of fundus in the observation group were lower than those in the control group (P＜0.05); The duration of blood lochia and serous lochia in the observation group was significantly shorter than that in the control group (P＜0.05); The quality of life score of the observation group was significantly higher than that of the control group  (P＜0.05); There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion The combination of Shenghua Decoction and Yimucao Granules is helpful to promote postpartum uterine involution, with high safety and certain clinical application value.

  一般产后5~6周子宫会逐渐恢复至非妊娠状态，该过程被称为子宫复旧，也叫产褥期。但由于子宫收缩、内膜再生障碍等原因，可能会造成子宫复旧不全[1]。产妇子宫复旧不全会引起下腹坠胀、腰痛、恶露时间延长，甚至会造成产褥感染，若得不到科学有效的治疗，可能会造成子宫功能永久性损伤，严重影响产妇身心健康。子宫复旧不全受多种因素的影响，相关研究提示与产妇年龄、生产方式、生产次数、喂养方式等均具有一定联系[2]。随着我国三胎生育政策的实施，子宫复旧不全发病率不断上升，受到越来越多关注。目前，尚缺少子宫复旧防治的规范化标准，临床上主要采用缩宫素、前列腺素类药物及垂体后叶素等药物进行对症治疗，虽然具有一定疗效，但毒副作用较大[3]。