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针灸治疗卵巢储备功能减退的临床研究进展

《中国中医药现代远程教育》[ISSN:1672-2779/CN:11-5024/R]

文章信息/Info

  • Title:针灸治疗卵巢储备功能减退的临床研究进展

  • 卷期:2024年22卷20期

  • 作者:孙欣瑜1,王平2,张英杰 3*

  • 1.山东中医药大学中医学院,山东济南,250014;2. 齐盛学校卫生保健科,山东淄博,255022;3.山东中医药大学健康学院,山东济南,250355

  • Author(s):SUN Xin-yu1, WHANG Ping 2, ZHANG Ying-jie 3*

  • 1. College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250014;2. Department of Health Care, Qisheng School, Zibo, Shandong, 255022;3. School of Health, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250355

  • 关键词针灸;卵巢储备功能减退;研究进展

  • Keywords: acupuncture; Diminished ovarian reserve; research progress;

  • 摘要: 通过检索近十年中国知网、维普、万方、PubMed数据库收录的关于针灸治疗卵巢储备功能减退的临床研究文献,笔者对相关研究进行梳理,总结针灸治疗卵巢储备减退的临床研究进展。通过整理发现,针灸、针药结合及针灸联合其他疗法对卵巢储备功能减退有较好的临床疗效,且具有操作简便、副作用小、不增加胃肠道以及肝肾负担等优点,值得在临床进一步推广。                                                                                                                                                                                

  • Abstract By searching the clinical research literature on acupuncture in the treatment of Diminished ovarian reserve included in CNKI, China Science and Technology Journal Database, WanFang Database and PubMed in the past ten years, the author sorted out the relevant studies and summarized the clinical research progress of acupuncture in the treatment of Diminished ovarian reserve. Through collation, it showed that acupuncture, acupuncture combined with medicine and acupuncture combined with other therapies have better clinical efficacy on Diminished ovarian reserve, and have the advantages of easy operation, less side effects and no increase in gastrointestinal tract as well as liver and kidney burden, which are worth further promotion in the clinic.

    卵巢储备功能减退(Diminished ovarian reserve,DOR)是指以卵巢中卵泡的数量或质量减退为主要特征,伴有抗苗勒管激素(AMH)、基础窦卵泡数(AFC)下降,基础促卵泡激素(FSH)升高,在临床上可表现为月经稀发、闭经、不孕或潮热盗汗等症状。DOR是卵巢功能初步减退的表现,可在1-6年内进展为卵巢早衰(premature ovarian failure,POF),加重对女性身心健康和生活质量的危害[1]。近些年,由于生活方式的改变和诊疗技术的发展,DOR的发病率正逐年增加[2]。现代医学对DOR的发病机理尚不十分清楚,认为DOR的发病与年龄、遗传因素、免疫因素、医源性因素、生活方式、心理压力及环境因素等相关[3]。西医主要采用激素替代治疗(HRT)治疗DOR,可明显改善月经及诸多低雌激素症状,但长期疗效不理想,不良反应和禁忌症多,且可增加罹患乳腺癌、卵巢癌等风险。

参考文献/References:

[1]Amanvermez R, Tosun M. An Update on Ovarian Aging and Ovarian Reserve Tests. Int J Fertil Steril. 2016,9(4):411-415.
[2]Pastore LM, Christianson MS, Stelling J, et al. Reproductive ovarian testing and the alphabet soup of diagnoses: DOR, POI, POF, POR, and FOR. J Assist Reprod Genet. 2018,35(1):17-23.
[3]Luderer U, Lim J, Ortiz L, et al. Exposure to environmentally relevant concentrations of ambient fine particulate matter (PM2.5) depletes the ovarian follicle reserve and causes sex-dependent cardiovascular changes in apolipoprotein E null mice. Part Fibre Toxicol. 2022,19(1):5.
[4]虞抟.医学正传[M].张丽君,丁侃,校注.北京:中国医药科技出版社,2011:222.

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