投稿热线:010-57289308
首页 >> 网络优先发表文章 >>文章 >> 孤独症谱系障碍的中西医治疗进展
详细内容

孤独症谱系障碍的中西医治疗进展

《中国中医药现代远程教育》[ISSN:1672-2779/CN:11-5024/R]

文章信息/Info

  • Title:Chinese and western medicine treatment progress of autism spectrum disorders

  • 卷期:2022年20卷01期

    • 作者:周莹莹1,3 刘勇2*,3

    • 1沈阳市儿童医院 康复医学科 辽宁 沈阳 110032;2 大连医科大学附属第一医院 康复医学科 辽宁 大连 116011;3 大连医科大学中西医结合学院/研究院 辽宁 大连 116050

    • Author(s):Zhou ying ying1,3,Liu yong2*,3

    • A children's hospital in shenyang liaoning shenyang 110032; 2 the first hospital affiliated to dalian medical university in dalian in liaoning 116011; 3 combine traditional Chinese and western medicine, dalian medical university school/institute of liaoning dalian 116050

    • 关键词:孤独症谱系障碍;中西医;治疗进展

    • Keywords: autism spectrum disorders; Chinese and western medicine. Treatment Progress

    • 摘要:孤独症谱系障碍是一组发病于生命早期,影响终身的神经发育障碍性疾病。近年来发病率持续增高,引起社会广泛关注。但因其病因病机仍不明确,治疗上缺乏针对性、统一性,尚无特效方法。近年来中西医结合疗法治疗孤独症谱系障碍取得了较好的临床疗效,通过大数据,查阅国内外大量文献,现将中医针灸、中药、五行音乐及西医行为教育、营养疗法、西药乃至新兴干细胞等治疗手段及治疗进展报道如下,从而为孤独症谱系障碍奠定深厚的诊疗和理论研究工作基础。                                                                                                                                                

    • Abstract:Objective:Autism spectrum disorders are a group of disease in the early life, affect the lifetime of neurodevelopmental disorder. In recent years the incidence of a disease continues to increase, a widespread social concern is caused. But because of its pathogenesis is still unclear, treatment on the lack of pertinence, unity, there is no specific method. Combine traditional Chinese and western medicine treatments for autism spectrum disorders in recent years have achieved good clinical effect, through the large data, a large number of literature at home and abroad will now, five lines of music and western medicine of traditional Chinese medicine acupuncture and moxibustion, behavior education, nutritional therapy, western medicine and emerging stem cell therapy and treatment progress reports as follows, such as for autism spectrum disorders deep theory of diagnosis and treatment and research foundation.                                                                                                                                                                                                                

      孤独症谱系障碍(Autism spectrum disorder,ASD)是严重危害儿童健康的神经发育障碍性疾病,多起病于婴幼儿时期。以持续存在的社会交往交流障碍、异常狭窄的兴趣范围或活动内容和行为表现刻板重复为核心特征,其作为广泛性神经发育障碍性疾病,更多共患症状如攻击性,强迫性,易激惹,肠胃问题以及睡眠障碍等,严重困扰患儿及其家庭。1943年,Kanner在临床病例报道中首次使用了“自闭症”。近年来,全世界ASD患病率持续升高。2000~2015年美国ASD患病率从1/150上升到1/45,男性高于女性,比例约为4~6:1。美国最新报道8岁儿童ASD患病率为1/59 。目前,其病因病机仍不明确,治疗手段极为有限。近年来文献报道中,中西医结合治疗ASD的临床疗效突出,逐渐成为主流治疗手段。

    参考文献/References:

    [1]Zablotsky B,Black LI,Maenner MJ,et al.Estimated prevalence of autism and other developmental disabilities following questionnaire changes in the 2014 national health interview survey[J].Natl Health Stat Report,2015,(87):1-20.
    [2]]BaioJ,WigginsL,ChristensenD,et al.Prevalence of autism Spectrum disorder among children Aged 8years-autismand Developmental disabilities monitoring network,11 sites,unitedstates,2014[J].MMWR,2018,67(6):1-23
    [3]李鹏,杜琳.孤独症谱系障碍中医研究进展[J].长春中医药大学学报,2019,35(05):1007-1009.
    [4] Jones Karen L,Van de Water Judy,Maternal autoantibody related autism: mechanisms and pathways[J].Mol. Psychiatry,2019,24(2): 252-265.
    [5]Liu Qiang,Chen Mo-Xian,Sun Lin et al.Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders[J].World J Stem Cells,2019,11(2):55-72.
    [6] de la Torre-Ubieta Luis,Won Hyejung,Stein Jason L et al.Advancing the understanding of autism disease mechanisms through genetics[J].Nat Med,2016,22(4):345–361.
    [7]Yang G, Shcheglovitov A.Probing disrupted neurodevelopment in autism using human stem cell-derived neurons and organoids:an outlook into future diagnostics and drug development[J].Dev Dyn,2019,249(1):6-33
    [8]American Psychiatric Association.Diagnostic and statistical manual of mentaldisorders[M].5th edition.Washington,DC:Author;2013.
    [9] 陈凯云,邓红珠,岑超群,等.孤独症谱系障碍儿童的局部脑血流灌注特点研究[J].新医学,2016,47(12):815-819.
    [10]高晓秋.“靳三针”针刺法治疗儿童自闭症50例效果观察[J].中国社区医师,2015,31(31):75-77.
    [11]赵勇,金炳旭,刘振寰.林氏头皮针治疗儿童自闭症临床观察[J].上海针灸杂志,2015,34(8):754-757.
    [12]李银枝,叶兵,张少平,等.中药辨证治疗自闭症的临床疗效观察[J].世界最新医学信息文摘,2019,19(99):3-4.
    [13]曲秀君,曹建英.中药治疗儿童自闭症30例临床疗效观察[J].中国现代药物应用,2019,13(17):103-104.
    [14]郝宏文,刘奕,卫利,等.王素梅治疗儿童自闭症经验[J].中医杂志,2016,57(01):19-21.
    [15]周念莹,李永春,江晓宇,等.理中汤加味治疗小儿自闭症临床观察[J].新中医,2015,47(6):200-202.
    [16]曹建英,曲秀君,王素丽,等.养心抗闭汤联合干预训练治疗心脾两虚型儿童自闭症的临床观察[J].河南中医,2019,39(6):898-900.
    [17]王冠.针灸推拿配合中医五行对自闭症患儿康复的干预研究[J].世界中西医结合杂志,2016,11(7):968-971
    [18]江玥婷,钱林霞,林法财.针灸联合五行音乐疗法在小儿自闭症中的应用探讨[J].中国民间疗法,2019,27(19):9-10.
    [19]黄凌一.五行音乐联合针刺推拿干预儿童自闭症随机平行对照研究[J].实用中医内科杂志,2018,32(06):66-68+77.
    [20]Goodarzi Parisa,Payab Moloud,Alavi-Moghadam Sepideh et al.Development and validation of Alzheimer's Disease Animal Model for the Purpose of Regenerative Medicine[J].Cell Tissue Bank,2019,20(2):141-151.
    [21]Smith Dean P,Hayward Diane W,Gale Catherine M et al.Treatment Gains from Early and Intensive Behavioral Intervention(EIBI)are Maintained 10 Years Later[J].Behav Modif, 2019,16(10):1-21.

    seo seo