补肾启枢强心颗粒治疗慢性心力衰竭的临床研究

文章信息/Info

• Title:补肾启枢强心颗粒治疗慢性心力衰竭的临床研究

• 卷期:2023年21卷24期

• 作者:邓鹏1，胡丹2，胡芳1，刘中勇1*

• 1.江西中医药大学附属医院心血管科，江西省南昌市东湖区八一大道445 号，330006； 2.上海中医药大学针推学院，上海市浦东新区蔡伦路1200号，201203

• Author(s):Deng Peng1, Hu Dan2, Hu Fang1, Liu Zhongyong1*

• 1.Department of Cardiology, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, 445 Bayi Avenue, Donghu District, Nanchang City, Jiangxi Province, 330006;2. School of Acupuncture, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong New Area, Shanghai, 201203

• 关键词慢性心力衰竭；补肾启枢强心颗粒；临床研究

• Keywords:chronic heart failure; Bushen Qishu Qiangxin granules; clinical research

• 摘要: 目的：观察补肾启枢强心颗粒对慢性心力衰竭的临床疗效。方法：选取120例江西中医药大学附属医院心血管科2019年1月至2020年12月住院患者。采用随机数字表分为治疗组和对照组各60例，对照组常规西药治疗，治疗组在常规西药治疗基础上加用补肾启枢强心颗粒，观察疗程8周。观察比较两组患者中医症候积分、左室射血分数、左室舒张末期内径、左室收缩末期内径、心功能分级变化、BNP水平、六分钟步行距离、明尼苏达生活质量量表调查积分等改善情况。结果：治疗组疗效明显优于对照组，P<0.05，具有可比性，差异有统计学意义。结论：补肾启枢强心颗粒治疗慢性心力衰竭临床疗效显著，值得推广应用。                                                                                                                                                                                

• Abstract: To observe the clinical effect of Bushen Qishu Qiangxin granule on chronic heart failure. Methods: A total of 120 patients hospitalized in the Department of Cardiology, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine from January 2019 to December 2020 were selected. 60 cases were randomly divided into treatment group and control group. The control group was treated with conventional western medicine, and the treatment group was treated with Bushen Qishu Qiangxin granule on the basis of conventional western medicine. The treatment course was observed for 8 weeks. Observe and compare the improvement of the two groups of patients' TCM syndrome score, left ventricular ejection fraction, left ventricular end-diastolic diameter, left ventricular end-systolic diameter, changes in cardiac function classification, BNP level, six-minute walk distance, and Minnesota quality of life scale survey points. Condition. Results: The efficacy of the treatment group was significantly better than the control group, the difference was statistically significant (P<0.05). Conclusion: Bushen Qishu Qiangxin Granules have significant clinical effects in the treatment of chronic heart failure and are worthy of popularization and application.

  慢性心力衰竭是心血管疾病终末阶段，再住院率及医疗费用高，且预后差，死亡率高。2010年美国卫生统计公布，心衰病人住院后30天病亡率和再住院率分别10.8%和24.5%[1]。全球范围每年消耗于慢性心力衰竭的费用为富有国家医疗总花费的1%-2%[2]。