卵巢储备功能减退的中西医病因分析及治疗现状研究

文章信息/Info

• Title:卵巢储备功能减退的中西医病因分析及治疗现状研究

• 卷期:2024年22卷1期

• 作者:黎源，靳艳文

• 桂林市中医医院妇科，广西 桂林，541000

• Author(s): LI Yuan，JIN Yan-wen

• Guilin Traditional Chinese Medicine Hospital，guangxi guilin541000，China

• 关键词卵巢储备功能减退；中西医治疗；病因病机

• Keywords:  Decreased ovarian reserve function; treatment by traditional Chinese and Western medicine; etiological mechanism

• 摘要:卵巢储备功能反映了女性生殖内分泌的潜能，取决于卵巢内库存卵泡的数量和质量，代表了卵巢皮质区卵泡生长、发育并形成可受精卵母细胞的能力。很多原因会引起女性卵巢储备功能的下降甚至过早衰退，从而出现月经改变、闭经、不孕及流产等生殖内分泌功能紊乱表现。现代医学对卵巢储备功能减退病因机制阐述颇多，临床治疗尚未统一，各种治疗方法均有一定的积极意义，但部分效果有待证实。中医从中药、针灸等方面着手，治疗优势逐渐凸显。                                                                                                                                                                                

• Abstract: Ovarian reserve function reflects the reproductive endocrine potential of women， depends on the number and quality of stocking follicles in the ovaries， and represents the ability of follicles in the ovarian cortical region to grow， develop and form fertilizable oocytes. Many reasons can cause the decline or even premature decline of women's ovarian reserve function， resulting in reproductive endocrine dysfunction such as menstrual changes， amenorrhea， infertility and miscarriage. Modern medicine has elaborated a lot on the etiology mechanism of hypoovarian reserve function， clinical treatment has not been unified， and various treatment methods have certain positive significance， but some effects have yet to be confirmed. Traditional Chinese medicine starts from traditional Chinese medicine， acupuncture and other aspects， and the advantages of treatment are gradually highlighted.

  卵巢储备功能（Ovarian Reservation，OR）是指在下丘脑-垂体-卵巢轴的控制下，卵巢皮质区卵泡生长、发育、形成可受精的卵母细胞的能力，反映了女性的生殖能力。随着女性年龄不断增长，卵巢内存余的卵母细胞数量减少、质量下降，进而导致女性卵巢储备功能减退（diminished ovarian reserve，DOR）、卵巢储备功能指标改变，从而致使女性生殖能力下降。如不早期干预，可进一步发展成早发性卵巢功能不全，更甚者可导致卵巢早衰（premature ovarian failure，POF）。