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中医药治疗膜性肾病研究进展

《中国中医药现代远程教育》[ISSN:1672-2779/CN:11-5024/R]

文章信息/Info

  • Title:中医药治疗膜性肾病研究进展

  • 卷期:2024年22卷1期

  • 作者:潘明珍1  杨钧朝1 吴雪华1  谢丽萍2

  • 1.广西中医药大学研究生院,广西南宁,530000; 2.广西中医药大学第一附属医院肾病科,广西南宁,530000

  • Author(s):Pan Mingzhen1  Yang Junchao1  Wu Xuehua1  Xie Liping2

  • 1.Guangxi University of Chinese Medicine   2.The First Affiliated Hospital of Guangxi University of Chinese Medicine

  • 关键词中医药;膜性肾病;研究;综述

  • Keywords:Traditional Chinese medicine;Membranous Nephropathy;research;review.

  • 摘要:膜性肾病(Membranous Nephropathy,MN)在临床上大部分可表现为肾病综合征(蛋白尿、低蛋白血症、水肿、高脂血症),也可以是无症状性的蛋白尿,发病率渐升,以中老年为主,并发症较多,中医药在治疗MN有着一定的优势。本文通过查阅近年来的文献,从病因病机、中药提取物、中成药、中药复方、外治法等方面作一综述,以期为中医药治疗MN提供一定的参考。                                                                                                                                                                                

  • Abstract:In clinic, most of Membranous Nephropathy (MN) showed nephrotic syndrome (proteinuria, hypoproteinemia, edema and hyperlipidemia), and asymptomatic proteinuria. The incidence of MN was increasing, mainly in the middle-aged and the elderly, with more complications. Traditional Chinese medicine had certain advantages in the treatment of MN. This article reviews the etiology and pathogenesis, Chinese medicine extract, Chinese patent medicine, Chinese medicine compound, external treatment and other aspects through reviewing the literature in recent years, in order to provide a certain reference for TCM treatment of MN.

    国内外文献报道,我国MN发病率较前上升,其中,在东北十年间的肾活检病理报告中,MN最为普遍,为29.1%[1,2]。MN可分为特发性膜性肾病(Idiopathic Membranous Nnephropathy,IMN)和继发性膜性肾病(Secondary Membranous Nnephropathy,SMN)。在肾小球的毛细血管基底膜下出现免疫复合物的弥漫性沉积引起肾小球基底膜增厚,是为MN在光镜下的病理特点[3]。

    参考文献/References:

    [1]Su S,Yu J,Wang Y, et al. Clinicopathologic correlations of renal biopsy fifindings from Northeast China: a 10-year retrospective study. Medicine (Baltimore) 2019;98:e15880.
    [2]TANG L,YAO J,KONG X,et al.Increasing prevalence of membranous nephropathy in patients with primary
    [3]史玉洁,翁亚菡.膜性肾病的病理学特点及诊断[J].中国临床医生杂志,2019,47(09):1020-1023.
    [4] 刘宝利,钟逸斐,刘伟敬,等.中医药临床优势病种探讨——膜性肾病[J].中国实验方剂学杂志,2021,27(16):185-190.
    [5]]李亚东. 张大宁教授治疗膜性肾病经验[J]. 光明中医,2018,33(13):1868-1869.

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