穴位贴敷对慢性疲劳综合征患者干预效果的Meta分析

文章信息/Info

• Title:穴位贴敷对慢性疲劳综合征患者干预效果的Meta分析*

• 卷期:2024年22卷1期

• 作者:魏炳琦1，祁帅党2，王心草2，李思慧1，李  菲3，张佳露1，马巧琳2、4*

• 1河南中医药大学中医学院（仲景学院），郑州 450046；2河南中医药大学针灸推拿学院，郑州 450046；3河南中医药大学医学院，郑州 450046；4河南中医药大学第三附属医院，郑州 450000

• Author(s):WEI bing-qi1QIshuai-dang2，WANG xin-cao2，LI si-hui1，LI fei3，ZHANG jia-lu1，MA qiao-lin2、4*

• 1College of Traditional Chinese Medicine ( Zhongjing College )，Henan University of Chinese Medicine，zhhengzhou 450046；2College of Acupuncture and Massage，Henan University of Chinese Medicine，zhhengzhou 450046；3Henan University of Chinese Medicine of Medicine，zhhengzhou 450046；4The Third Affiliated Hospital of Henan University of Chinese Medicine, zhhengzhou 450000

• 关键词穴位贴敷；慢性疲劳综合征；总有效率；显效率；Meta分析；GRADE；证据等级；循证医学

• Keywords:acupoint application ; chronic fatigue syndrome ; total efficiency ; significant efficiency ; meta-analysis ; GRADE ; evidence level ; evidence medicine

• 摘要:目的：系统评价穴位贴敷在中医外治慢性疲劳综合征中的干预效果。方法：在数据库中检索穴位贴敷干预慢性疲劳综合征的随机对照试验，采用RevMan软件分析。结果：共纳入7篇文献，481例患者。Mete分析结果：①单纯穴位贴敷、穴位贴敷联合其它疗法与各对照组的显效率结果分别为[OR=3.93，95%CI（1.33,11.58），P<0.05]、[OR=2.56，95%CI（1.33,4.93），P<0.01]均具有统计学意义。②单纯穴位贴敷、穴位贴敷联合其它疗法与对照组在总有效率相比[OR=9.45，95%CI（4.36,20.47），P<0.01]、[OR=7.45，95%CI（3.37,16.49），P<0.01]均具有统计学意义。结局指标评分级证据评价评为“极低级”。结论：穴位贴敷在干预慢性疲劳综合征的总有效率和显效率上具有优势，但临床上仍需更多高质量、多中心的随机对照试验。                                                                                                                                                                                

• Abstract:systematically evaluate the intervention effect of acupoint application in TCM external treatment of chronic fatigue syndrome. Methods : Randomized controlled trials of acupoint application on chronic fatigue syndrome were searched in the database and analyzed by RevMan software. Results : A total of 7 articles were included, with 481 patients. Mete analysis results : 1 The significant efficiency results of simple acupoint application, acupoint application combined with other therapies and each control group were [ OR = 3.93,95 % CI ( 1.33,11.58 ), P < 0.05 ], [ OR = 2.56,95 % CI ( 1.33,4.93 ), P < 0.01 ]. 2 Compared with the control group, the total effective rates of simple acupoint application, acupoint application combined with other therapies were statistically significant [ OR = 9.45, 95 % CI ( 4.36, 20.47 ), P < 0.01 ] and [ OR = 7.45, 95 % CI ( 3.37, 16.49 ), P < 0.01 ]. The score-level evidence evaluation of outcome indicators was rated as “ extremely low ”. Conclusion : Acupoint application has advantages in the total effective rate and significant efficiency of chronic fatigue syndrome intervention, but more high-quality, multi-center randomized controlled trials are still needed in clinic.

  慢性疲劳综合征(chronic fatigue syndrome，CFS)是一种病因不明的衰弱性疾病，无标准治疗方法，症状和临床病程在有或没有治疗干预的情况下可能会发生波动，医疗需求高[1-3]。其主要表现为严重疲劳等，归属于中医学“虚劳”范畴[4]。目前，在高压力、不良情志、在饮食习惯等多种因素影响下发病率呈上升趋势，生活、学业压力大及高强度工作人群为慢性疲劳综合征的好发人群[5-6]。