杞菊地黄汤联合通窍明目针法治疗糖尿病视网膜病变的临床疗效观察

文章信息/Info

• Title:杞菊地黄汤联合通窍明目针法治疗糖尿病视网膜病变的临床疗效观察

• 卷期:2024年22卷2期

• 作者:吴丹

• 中国医科大学附属盛京医院眼科 辽宁沈阳 110000

• Author(s): Wu Dan

• Department of Ophthalmology, Shengjing Hospital Affiliated to China Medical University, Shenyang, Liaoning 110000

• 关键词杞菊地黄汤；通窍明目针法；糖尿病视网膜病变；临床疗效

• Keywords:Qi Ju Di Huang Tang；Tong Qiao Ming Mu acupuncture；diabetic retinopathy；clinical efficacy

• 摘要:目的：探讨杞菊地黄汤联合通窍明目针法治疗糖尿病视网膜病变（DR）的临床疗效。方法：将98例非增殖期DR患者随机分为对照组49例和试验组49例。对照组予以常规治疗及羟苯磺酸钙胶囊，试验组在对照组基础上予以杞菊地黄汤联合通窍明目针法治疗。2组患者治疗时间均为8周。比较2组临床疗效，视网膜渗漏总面积及毛细血管无灌注区总面积，黄斑区视网膜平均厚度（CAT）、体积（CV）及中央区厚度（CST）。结果：治疗后试验组总有效率高于对照组（P＜0.05）。与对照组比较，试验组治疗后视网膜渗漏总面积及毛细血管无灌注区总面积较低，黄斑区CAT、CV及CST较低（P＜0.05）。结论：杞菊地黄汤联合通窍明目针法能明显改善DR患者眼底视网膜微血管病变，缓解黄斑区视网膜水肿，临床疗效显著。                                                                                                                                                                                

• Abstract: To investigate the clinical efficacy of Qi Ju Di Huang Tang combined with Tong Qiao Ming Mu acupuncture in the treatment of diabetic retinopathy（DR）. Methods: 98 patients with non proliferative DR were randomly divided into control group with 49 cases and treatment group 49 cases. The control group was treated with routine treatment and calcium dobesilate capsules, and on the basis of the control group，the treatment group was treated with Qi Ju Di Huang Tang combined with Tong Qiao Ming Mu acupuncture based on midnight-noon ebb-flow acupoint selection. The treatment time of the two groups were both 8 weeks. The clinical efficacy，total area of retinal leakage and total area of capillaries without perfusion, cube average thickness (CAT), cube volume (CV) and central sufield thickness (CST) in macular region were compared between the 2 groups. Results: After treatment，the total effective rate of the treatment group was higher than that of the control group (P<0.05). Compared with the control group, the total area of retinal leakage and total area of capillaries without perfusion were lower，the CAT，CV in macular region and CST were lower in the treatment group after treatment(P<0.05). Conclusion: Qi Ju Di Huang Tang combined with Tong Qiao Ming Mu acupuncture can significantly improve the retinal microangiopathy of patients with DR，alleviate the retinal edema in the macular area，and the clinical effect is remarkable.

  糖尿病视网膜病变(Diabetic retinopathy，DR) 属糖尿病常见的微血管并发症，近年来发病率随糖尿病发病率的上升而不断增加，资料显示[1]，2017年我国糖尿病患者中有27.9%左右受到DR困扰，其中12.6%视力受损，而发病率逐年上升的同时还有年轻化趋势。DR通常分为非增殖期和增殖期两个阶段，非增殖期以眼底微血管瘤出现、硬性渗出、出血点等为主要表现，增殖期则以异常新生血管形成为特征，一旦发展到增殖期，很容易导致患者失明，故早期有效的治疗尤为重要。