桂枝甘草龙骨牡蛎加味汤治疗室性早搏的临床效果

文章信息/Info

• Title:桂枝甘草龙骨牡蛎加味汤治疗室性早搏的临床效果

• 卷期:2024年22卷4期

• 作者:刘勤1   赖晓霖2  李毅然3

• 1万安县人民医院心电图室  江西吉安   343800；2万安县中医院内科  江西吉安   343800；3万安县人民医院心血管内科 江西吉安   343800

• Author(s):Liu Qin1 Lai Xiaolin2 Li Yiran3

• 1. ECG Room, Wan'an County People's Hospital, Ji'an, Jiangxi；2 Wan'an County Hospital of Traditional Chinese Medicine, Ji'an, Jiangxi；3.Department of Cardiovascular Medicine, Wan'an County People's Hospital, Ji'an, Jiangxi

• 关键词室性早搏；治疗效果；桂枝甘草龙骨牡蛎加味汤

• Keywords:ventricular premature beat; therapeutic effect; Guizhi Gancao Longgu Muli Jiawei Decoction

• 摘要:目的：探究分析对室性早搏患者，积极给予桂枝甘草龙骨牡蛎加味汤治疗，详细分析取得的结果。方法：80例室性早搏患者，2020年3月至2022年3月，随机分为观察组：桂枝甘草龙骨牡蛎加味汤，对照组：中医常规方法，各40例。比较分析24 h 动态心电图室性早搏总数、中医证候积分、临床疗效、不良反应、 心率减速力。结果：治疗后观察组中医证候积分低于对照组，有统计学意义（P＜0.05）；观察组治疗总有效率38例（95.00%）高于对照组28例（7.00%），有统计学意义（P＜0.05）；观察组的恶心、头晕、腹部不1例（2.50%）明显低于对照组的9例（22.50%），有统计学意义（P＜0.05）；观察组的心率减速力较对照组提升，降低24h 动态心电图室性早搏总数（P＜0.05）。结论：经积极的把桂枝甘草龙骨牡蛎加味汤治疗用于室性早搏患者，降低不良反应的发生，提升心率减速力，改善中医证候积分，安全性较高，降低24 h 动态心电图室性早搏总数，适合应用于临床推广。                                                                                                                                                                                

• Abstract:To explore and analyze the patients with premature ventricular contractions, actively give Guizhi Gancao Longgu Muli Jiawei Decoction treatment, and analyze the results in detail. Methods: 80 patients with premature ventricular contractions, from March 2020 to March 2022, were randomly divided into the observation group: Guizhi Gancao Longgu Muli Jiawei Decoction, and the control group: the conventional method of traditional Chinese medicine, 40 cases in each group. The total number of premature ventricular contractions, TCM syndrome scores, clinical efficacy, adverse reactions and heart rate deceleration in 24 hours were compared and analyzed. Results: After treatment, the TCM syndrome scores of the observation group were lower than those of the control group, with statistical significance (P<0.05). The incidence of nausea, dizziness and abdominal pain in the observation group (2.50%) was significantly lower than that in the control group in 9 cases (22.50%), with statistical significance (P<0.05); the heart rate of the observation group was significantly lower (P<0.05). The deceleration force was higher than that of the control group, and the total number of premature ventricular contractions in the 24-hour dynamic ECG was decreased (P<0.05). Conclusion: Guizhi Gancao Longgu Muli Jiawei Decoction is actively used in the treatment of patients with premature ventricular contractions, which can reduce the occurrence of adverse reactions, improve the heart rate deceleration ability, and improve the TCM syndrome score. The total number of premature beats is suitable for clinical promotion.

  造成心源性猝死的一项关键因素就是室性早搏，且在当前的临床中，室性早搏有较高的致死率，病因复杂，是常见疾病。西医治疗一般选择抗心律失常药物，但是取得的疗效较差，存在一定不良反应。在中医学中此病疾病归属于心悸等范畴，病因同年老体虚、久病失养、外邪入侵、劳逸过度、药物、情志失调等存在密切关联性，且心脉痹阻、阳微阴弦是主要病机[1]。针对于室性早搏，气虚血瘀证是常见中医证型，坚持的治疗原则为补气、活血、安神。中医药治疗室性早搏患者时，通过之前的研究显示出，桂枝甘草龙骨牡蛎加味汤较为常见。