补益宗气法治疗慢性阻塞性肺疾病稳定期患者的临床研究

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• Title:补益宗气法治疗慢性阻塞性肺疾病稳定期患者的临床研究

• 卷期:2024年22卷13期

• 作者:黄丹  周卫民  甘桃梅  李建华

• 九江市中医医院,重症医学科，江西 九江 332000

• Author(s):Huang Dan, Zhou Weimin, Gan Taomei, Li Jianhua

• Jiujiang Traditional Chinese Medicine Hospital.Department of Critical Care Medicine.Jiujiang City, Jiangxi Province 332000 China

• 关键词补益宗气；慢性阻塞性肺疾病稳定期；肺功能；血气分析

• Keywords: Reinforce Zongqi; Stable period of chronic obstructive pulmonary disease; Lung function; Blood gas analysis

• 摘要:目的：拟通过补益宗气法治疗慢阻肺稳定期患者的临床研究，观察补益宗气法对慢阻肺稳定期患者肺功能（FEV1、FEV1/FVC%）及血气分析（PaO2 、PaCO2）指标的影响，探讨补益宗气法防治慢性阻塞性肺疾病的部分作用机制。方法：选择门诊慢阻肺稳定期患者60例，随机将其分为观察组和对照组各30例。两组均给予沙美特罗替卡松粉吸入剂治疗，1吸／次，2次／d；观察组在对照组西医治疗基础上联合服用补元汤；两组观察时间均为6个月，观察两组患者治疗前后患者肺功能及血气分析指标的改善情况；结果治疗6个月后，两组患者FEV1、FEV1/FVC%、PaO 2均高于治疗前，观察组显著高于对照组，而两组PaCO 2 水平均低于治疗前，观察组显著低于对照组（P<0.05）。结论：补益宗气法，能够改善慢阻肺稳定期患者肺功能及血气分析指标，为防治该病提供了新思路和方法。                                                                                                                                                                                

• Abstract To conduct a clinical study on the treatment of patients with chronic obstructive pulmonary disease (COPD) in stable stage by supplementing Zongqi,To observe the effect of tonifying Zongqi method on pulmonary function (FEV1, FEV1/FVC%) and blood gas analysis (PaO2, PaCO2) in patients with chronic obstructive pulmonary disease (COPD) in stable stage,To explore the partial mechanism of the method of invigorating Zongqi in preventing and treating chronic obstructive pulmonary disease (COPD).Methods: 60 outpatients with COPD in stable stage were selected,They were randomly divided into observation group and control group with 30 cases each.Both groups were treated with salmeterol and fluticasone powder inhalation, once a time, twice a day;The observation group took Buyuan decoction on the basis of western medicine treatment in the control group;The observation time of both groups was 6 months,Observe the improvement of pulmonary function and blood gas analysis indexes of patients in both gyoups before and after treatment;Results After 6 months of treatment, FEV1, FEV1/FVC% and PaO 2 in both groups were higher than those before treatment,The level of PaCO 2 in the observation group was significantly higher than that in the control group, while the level of PaCO 2 in both groups was lower than that before treatment,The observation group was significantly lower than the control group (P<0.05).Conclusion: The method of tonifying Zongqi can improve the lung function and blood gas analysis indexes of patients with COPD in stable stage, providing new ideas and methods for the prevention and treatment of the disease.

  COPD归属于中医“肺胀”范畴，肺胀名称，始载于《内经》。《金匮要略》曰：“上气喘而躁者，属肺胀”，“咳而上气，此为肺胀，其人喘，目如脱状”，形象论述了该病的临床特征。国医大师洪广祥教授根据COPD患者动则喘甚、呼吸肌疲劳、营养障碍等特征，认为COPD患者普遍存在营养障碍的情况，是源于宗气虚衰，元气得不到宗气充养，元气不足，肺脾肾气虚，水谷精微得不到运化，机体供给营养缺乏，脏腑及肌肤失养，又肺气胀满，胸部憋闷膨满，呼吸表浅，喘息上气，呼吸浅短难续，呼吸过度，张口抬肩，伤津耗气，身体羸弱，逐渐消瘦。