中药熏蒸加氯诺昔康治疗腰推间盘突出症62例的临床疗效观察

文章信息/Info

• Title:中药熏蒸加氯诺昔康治疗腰推间盘突出症62例的临床疗效观察

• 卷期:2024年22卷14期

• 作者:江小平

• 南丰县中医院骨伤科，江西 抚州 344500

• Author(s):Jiang Xiaoping

• Department of Orthopedics and Traumatology, Nanfeng County Hospital of Traditional Chinese Medicine, Fuzhou, Jiangxi 344500

• 关键词腰推间盘突出症；中药熏蒸；氯诺昔康；疼痛程度；腰椎功能

• Keywords:Lumbar disc herniation; Fumigation of traditional Chinese medicine; Lornoxicam; Pain; Lumbar function

• 摘要:目的  探讨腰推间盘突出症（LDH）患者应用中药熏蒸加氯诺昔康治疗的效果。方法  采用随机数字表法将2019年1月至2021年12月我院收治的124例LDH患者分为两组，每组各62例。对照组予以氯诺昔康治疗，观察组加用中药熏蒸治疗，均连续治疗10d。比较两组临床疗效、腰椎功能、疼痛程度、日常生活能力、血清学指标及不良反应。结果  治疗后，观察组临床总有效率、日本骨科协会评估治疗分数（JOA）、日常生活活动能力（ADL）评分较对照组高，视觉模拟评分（VAS）评分及肿瘤坏死因子α（TNF-α）、重组人基质金属蛋白酶3（MMP-3）水平较对照组低，有统计学差异（P＜0.05）；两组未见严重不良反应。结论  LDH患者应用中药熏蒸加氯诺昔康治疗可减轻炎症反应，改善椎功能及日常生活活动能力，降低TNF-α、MMP-3水平，效果显著，安全性好，值得临床推广。                                                                                                                                                                                

• AbstractTo investigate the effect of herbal fumigation plus lornoxicam on patients with lumbar disc herniation (LDH). Methods 124 patients with LDH admitted to our hospital from January 2019 to December 2021 were randomly divided into two groups, 62 in each group. The control group was treated with lornoxicam, and the observation group was treated with traditional Chinese medicine fumigation for 10 consecutive days. The clinical efficacy, lumbar function, pain degree, daily living ability, serological indexes and adverse reactions of the two groups were compared. Results After treatment, the total clinical efficiency, JOA, ADL, VAS and TNF in the observation group were higher than those in the control group α （TNF- α）、 The level of recombinant human matrix metalloproteinase-3 (MMP-3) was significantly lower than that of the control group（P＜0.05）; No serious adverse reaction was found in the two groups. Conclusion The traditional Chinese medicine fumigation plus lornoxicam can reduce inflammatory reaction, improve vertebral function and activities of daily living, and reduce TNF in patients with LDH- α、 The level of MMP-3, with significant effect and good safety, is worthy of clinical promotion.

  腰推间盘突出症（LDH）是临床常见病、多发病，其发生与年龄、负重情况、外伤、职业等因素有关，以腰背部疼痛、活动障碍为主要表现，可伴下肢放射性疼痛，好发于青壮年中，对其生活、工作造成较大的影响[1]。对于无手术指征的患者临床多主张保守治疗，西医主要采用止痛、激素类药物以缓解患者疼痛，虽有一定的效果，但存在一定的副作用，且易复发，整体效果欠佳。中药熏蒸以中医理论为指导，通过中药煎煮所产生的蒸汽微粒熏蒸人体表面，以达到防治疾病的目的，已被广泛应用于多种疾病治疗中[2]。