中药材辐射灭菌研究进展

文章信息/Info

• Title:中药材辐射灭菌研究进展

• 卷期:2024年22卷15期

• 作者:刘少雄1，聂武芳2，袁源见1，郑佳莉3，王李俊1※

• 1. 江西中医药高等专科学校 药学系，江西抚州 344000；2. 江西中医药高等专科学校 图书馆，江西抚州 344000；3. 江西中医药高等专科学校 医学基础部，江西抚州 344000

• Author(s):LIU Shaoxiong1, NIE Wufang2, YUAN Yuanjian1, ZHENG Jiali3, WANG Lijun1※

• (1. Department of Pharmacy, Jiangxi College of Traditional Chinese Medicine, Fuzhou 344000, Jiangxi, China; 2. Library, Jiangxi College of Traditional Chinese Medicine, Fuzhou 344000, Jiangxi, China; 3. Department of Basic Medical, Jiangxi College of Traditional Chinese Medicine, Fuzhou 344000, Jiangxi, China

• 关键词中药材；辐射；灭菌

• Keywords:Chinese herbal medicine; Radiation; Sterilization

• 摘要:应用辐射灭菌技术，特别是电子束辐射，用于中药材的辐照灭菌，对于提高中药材的质量、确保中药材的安全具有重大意义。将会对我国中药材的灭菌方法进一步的完善，从而带来较好的经济效益和社会效益。本文从辐照灭菌的安全性、对中药材有效成分影响、对中药材外观形状的影响、种类、剂量及储存条件等方面进行总结，以期为中药材辐射灭菌提供依据。                                                                                                                                                                                

• Abstract The application of radiation sterilization technology, especially electron beam radiation, to the irradiation sterilization of Chinese medicinal materials is of great significance for improving the quality of Chinese medicinal materials and ensuring the safety of Chinese medicinal materials. It will further improve the sterilization method of Chinese herbal medicine, thus bringing better economic and social benefits. This paper summarized the safety of irradiation sterilization, the impact on the effective components of Chinese medicinal materials, the impact on the appearance of Chinese medicinal materials, types, dosage and storage conditions, so as to provide a basis for the radiation sterilization of Chinese medicinal materials.

  中药材辐射灭菌是使用电离辐射（主要是指Co-γ射线、加速器产生的电子束或X射线）与中药材中细菌、病毒、害虫等的相互作用产生的物理、化学和生物效应，使得其中的细胞核，尤其是DNA被直接击中，发生断裂、破坏等导致死亡，从而使得中药材达到灭菌效果[1-3]。