清火消痈汤治疗慢性肺痈(心肝火旺,热毒内蕴证)的临床价值分析

文章信息/Info

• Title:清火消痈汤治疗慢性肺痈(心肝火旺,热毒内蕴证)的临床价值分析

• 卷期:2024年22卷18期

• 作者:潘延成

• 滕州市中心人民医院药学部  山东滕州  277599

• Author(s):Pan Yancheng

• Pharmacy Department of Tengzhou Central People's Hospital

• 关键词清火消痈汤；慢性肺痈；心肝火旺；热毒内蕴证；疗效；症状积分

• Keywords: clear fire and eliminate carbuncle soup; chronic lung carbuncle; heat and poison accumulation; curative effect; symptom score

• 摘要:目的：研究慢性肺痈(心肝火旺,热毒内蕴证)选择清火消痈汤的治疗价值。方法：2021年1月-2021年12月为研究周期跨度，抽取研究对象72例，采用病历号数字表分组法随机分组为研究组（n=36）、对照组（n=36），对照组实施西药治疗，研究组实施清火消痈汤治疗，对比两组呼吸功能、症状积分。结果：对比两组治疗后PaCO2指标，研究组（41.42±3.75）mmHg低于对照组（47.59±5.88）mmHg，（P＜0.05）；PaO2指标对比，研究组（82.99±6.75）高于对照组（73.26±2.48），（P＜0.05）；对比两组治疗后主症积分（2.44±0.68）、次症积分（0.65±0.11）、临床症状总积分（3.12±0.64），研究组均低于对照组（5.29±1.05）、（1.89±0.62）、（7.28±1.75）（P＜0.05）。结论：清火消痈汤治疗慢性肺痈，疗效显著。                                                                                                                                                                                

• Abstract  To study the therapeutic value of chronic lung carbuncle (heat toxicity). Methods: From January 2021 to December 2021, as the study cycle span, 72 study subjects were selected, and the medical record number table method was randomly divided into the study group (n=36) and the control group (n=36), the control group was treated with western medicine, the control group was treated with fire removal and carbuncle removal, and the respiratory function and symptom points were compared between the two groups. Results: Comparing the treatment PaCO2 index between the two groups, The study group (41.42 ± 3.75) mmHg was lower than the control group (47.59 ± 5.88) mmHg, (P<0.05); For the PaO 2 index comparison, The study group (82.99 ± 6.75) was higher than the control group (73.26 ± 2.48), (P<0.05); Compare the two post-treatment primary disease points (2.44 ± 0.68), secondary disease points (0.65 ± 0.11), and total clinical symptoms points (3.12 ± 0.64), The study groups were all lower than the control group (5.29 ± 1.05), (1.89 ± 0.62), and (7.28 ± 1.75) (P <0.05). Conclusion: The treatment of the chronic lung carbuncle is remarkable.

  近年来，支气管扩张治疗、病因机制方面，中西医均取得了显著进步。现代医学中，关于急性加重期支气管扩张治疗方案较多，疗效均较好，但针对慢性期治疗并无确切的治疗方案，大部分医生会选择长期低剂量口服抗菌药物，对这类药物的作用机制、靶点作用、相关毒性问题并无明确，针对慢性支扩患者临床病症、发作周期等方面的研究较少。既往中医认为，慢性支气管扩张属于“肺痈”范畴，其认为病因为“热毒”，治疗应当以清热、凉血、排毒、消痈、排脓为主，忽略了该病的本质，未能考虑脏腑理论[2]。